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The following sources are referenced in UbiCare’s Cord Blood Banking Awareness Program, a series of four emails and 26 social media posts.

References in Email 1 – Will you discard a potential lifesaver?

Foot Note 1 – Claim: Today, cord blood stem cells can be used to treat nearly 80 disorders.  Source: Moise K Jr. Umbilical cord stem cells. Obstet Gynecol.2005;106(6):1393–1407

Foot Note 2 – Claim: Cord blood stem cells have been used in treatment for over 20 years.  Source: Wagner, Gluckman. Umbilical cord blood transplantation: the first 20 years. Seminars in Hematology. 47(1):3-12 2010.

Foot Note 3 – Claim: Cord blood stem cells can treat certain cancers, bone marrow failure syndromes, blood disorders, metabolic disorders, and immunodeficiencies, among other diseases.  Source: O’Brien TA, Tiedemann K, Vowels MR. No longer a biological waste product; umbilical cord blood. Med J Aust. 2006; 184(8): 407-410.

Foot Note 4 – Claim: Cord blood stem cells can treat certain cancers, bone marrow failure syndromes, blood disorders, metabolic disorders, and immunodeficiencies, among other diseases.  Source: Harris DT, Collection, processing, and banking of umbilical cord blood stem cells for clinical use in transplantation and regenerative medicine. Lab Med. 2009; 39(3):173-178.

Foot Note 5 – Claim: Clinical studies are now underway on the use of cord blood stem cells in the treatment of cerebral palsy and brain and spinal cord injuries.  Source: Harris DT, Badowski M, Ahmad N, Gaballa MA. The potential of cord blood stem cells for use in regenerative medicine. Expert Opin Biol Ther. 2007;7(9):1311–1322.

Foot Note 6 – Claim: Clinical studies are now underway on the use of cord blood stem cells in the treatment of Alzheimer’s disease.  Source: Lee et al. The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer’s disease. Neurosci Lett. 2010 Aug 30;481(1):30-5. Epub 2010 Jun 19.

Foot Note 7 – Claim: Clinical studies are now underway on the use of cord blood stem cells in the treatment of heart disease.  Source: Dayan V, Yannarelli G, Billia F, et al. Mesenchymal stromal cells mediate a switch to alternatively activated monocytes/macrophages after acute myocardial infarction. Basic Res Cardiol. 2011;106(6):1299–1310.

 

References in Email 2 – Cord blood banking:  2 options, 1 opportunity

Foot Note 1 – Claim: Cost of public donation and retrieval from a public cord blood stem cell registry.  Source: National Cord Blood Program online, accessed March 29, 2012.

Foot Note 2 – Claim: Cost of public donation and retrieval from a public cord blood stem cell registry.  Source: National Marrow Donor Program online. Accessed June 20, 2012.

Foot Note 3 – Claim: About 70% of cord blood units collected for public donation are not stored fro transplant.  Source: Moise K Jr. Umbilical cord stem cells. Obstet Gynecol. 2005;106(6):1393–1407.

 

References in Email 3 – How cord blood banking works

Foot Note 1 – Claim: There is a 25%–75% chance that banked cord blood stem cells will be an acceptable match for a sibling.  Source: Beatty PG, Boucher KM, Mori M, Milford EL.Probability of finding HLA-mismatched related or unrelated marrow or cord blood donors. Hum Immunol. 2000;61(8):834–840.

Foot Note 2 – Claim: Cord blood stem cell transplants from a family member have been shown to be about twice as successful as those from an unrelated donor.  Source: Gluckman E, Rocha V, Boyer-Chammard A, et al. Outcome of cord-blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Transplantation Group. N Engl J Med. 1997; 337:373-381.

 

References in Email 4 – Have you made a plan?

Foot Note 1 – Claim: It is estimated that 1 in 217 people may need a stem cell transplant by the age of 70 using stem cells from umbilical cord or bone marrow.  Source: Nietfeld JJ, Pasquini MC, Logan BR, Verter F, Horowitz MM. Lifetime probabilities of hematopoietic stem cell transplantation in the U.S. Biol Blood Marrow Transplant. 2008;14(3):316–322.

Foot Note 2 – Claim: The odds that someone would use stem cells from cord blood or bone marrow for regenerative medicine by the age of 70 have been estimated to be 1 in 3.  Source: Harris DT. Cord blood stem cells: a review of potential neurological applications. Stem Cell Rev. 2008;4:269-274. Epub August 5, 2008.

Foot Note 3 – Claim: Research shows that umbilical cord blood stem cells can be stored for more than 20 years without loss of viability.  Source: Broxmeyer HE, et al. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21 – 23.5-year cryopreserved cord blood. Blood. 2011. 117(18): 4773-4777. doi:10.1182/blood-2011-01-330514

 

 

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